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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK1
All Species:
19.7
Human Site:
S358
Identified Species:
33.33
UniProt:
O60285
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60285
NP_055655.1
661
74305
S358
G
L
A
K
P
T
T
S
E
V
M
L
E
R
Q
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
S358
G
L
A
K
P
T
T
S
E
V
M
L
E
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001098986
667
74748
S364
G
L
V
K
P
T
T
S
E
V
M
L
E
R
Q
Dog
Lupus familis
XP_538417
666
74288
S363
G
L
A
K
P
G
A
S
E
V
M
L
E
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q641K5
658
73643
S359
G
L
A
K
P
G
A
S
E
V
V
L
E
R
Q
Rat
Rattus norvegicus
Q66HE5
630
69934
A337
D
S
G
R
A
S
M
A
D
W
L
R
R
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508265
661
73136
A358
A
K
A
G
S
S
E
A
P
L
E
R
Q
R
S
Chicken
Gallus gallus
Q9IA88
798
88848
S350
R
L
K
E
Y
R
S
S
Q
L
S
S
R
P
A
Frog
Xenopus laevis
NP_001088596
570
64876
N277
V
A
S
H
W
W
V
N
W
G
Y
T
Q
P
L
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
G680
Q
A
L
S
L
G
H
G
E
N
Q
P
S
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649991
1427
153426
N981
C
N
S
S
N
I
G
N
C
N
T
M
P
Y
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
V524
G
V
I
T
R
E
H
V
T
S
S
S
A
S
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
F218
L
L
C
G
T
L
P
F
D
D
E
N
I
P
N
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
S337
N
D
S
K
K
D
G
S
S
P
D
N
D
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.7
N.A.
90.9
55.6
N.A.
84.2
26.1
48.5
23.5
N.A.
24.3
N.A.
22.4
N.A.
Protein Similarity:
100
99.8
98
94.4
N.A.
93.8
68
N.A.
88
42.8
61.4
36.2
N.A.
33.6
N.A.
35.8
N.A.
P-Site Identity:
100
93.3
93.3
86.6
N.A.
80
0
N.A.
13.3
13.3
0
6.6
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
33.3
N.A.
40
40
20
6.6
N.A.
20
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
36
0
8
0
15
15
0
0
0
0
8
0
8
% A
% Cys:
8
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
8
0
0
15
8
8
0
8
0
0
% D
% Glu:
0
0
0
8
0
8
8
0
43
0
15
0
36
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
43
0
8
15
0
22
15
8
0
8
0
0
0
0
8
% G
% His:
0
0
0
8
0
0
15
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
8
0
0
8
0
0
0
0
0
0
8
0
8
% I
% Lys:
0
8
8
43
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
50
8
0
8
8
0
0
0
15
8
36
0
0
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
29
8
0
0
0
% M
% Asn:
8
8
0
0
8
0
0
15
0
15
0
15
0
0
8
% N
% Pro:
0
0
0
0
36
0
8
0
8
8
0
8
8
22
0
% P
% Gln:
8
0
0
0
0
0
0
0
8
0
8
0
15
8
36
% Q
% Arg:
8
0
0
8
8
8
0
0
0
0
0
15
15
36
0
% R
% Ser:
0
8
22
15
8
15
8
50
8
8
15
15
8
22
15
% S
% Thr:
0
0
0
8
8
22
22
0
8
0
8
8
0
0
0
% T
% Val:
8
8
8
0
0
0
8
8
0
36
8
0
0
0
8
% V
% Trp:
0
0
0
0
8
8
0
0
8
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _